2-(4-OXO-2-THIOXO-THIAZOLIDIN-3-YL)-SUCCINIC ACID synthesis
- Product Name:2-(4-OXO-2-THIOXO-THIAZOLIDIN-3-YL)-SUCCINIC ACID
- CAS Number:31316-80-0
- Molecular formula:C7H7NO5S2
- Molecular Weight:249.26
75-15-0
253 suppliers
$40.00/100g
3926-62-3
287 suppliers
$19.73/250g
617-45-8
436 suppliers
$5.00/25g
31316-80-0
15 suppliers
$199.97/250mg
Yield:31316-80-0 75%
Reaction Conditions:
Stage #1: carbon disulfide;aspartic Acidwith potassium hydroxide in lithium hydroxide monohydrate at 20; for 1 h;
Stage #2: chloroacetic acid sodium salt in lithium hydroxide monohydrate at 20; for 12 h;
Stage #3: with hydrogenchloride in lithium hydroxide monohydrate; for 1 h;Reflux;
References:
Finiuk, Nataliya;Kryshchyshyn-Dylevych, Anna;Holota, Serhii;Klyuchivska, Olga;Kozytskiy, Andriy;Karpenko, Olexandr;Manko, Nazar;Ivasechko, Iryna;Stoika, Rostyslav;Lesyk, Roman [European Journal of Medicinal Chemistry,2022,vol. 238,art. no. 114422]