ChemicalBook CAS DataBase List 2,5-DIBROMO-3,4-DINITROTHIOPHENE

2,5-DIBROMO-3,4-DINITROTHIOPHENE synthesis

4synthesis methods

Product Name:2,5-DIBROMO-3,4-DINITROTHIOPHENE
CAS Number:52431-30-8
Molecular formula:C4Br2N2O4S
Molecular Weight:331.93

3141-27-3 Synthesis

3141-27-3
308 suppliers
$5.00/10g

52431-30-8
188 suppliers
$24.00/1g

Yield:52431-30-8 88%

Reaction Conditions:

with sulfuric acid;HNO₃ in lithium hydroxide monohydrate at 20 - 30; for 4 h;Cooling with ice;

Steps:

2 2,5-dibromo-3,4-dinitrothiophene

Compound 5 was prepared according to the procedure reported (Mozingo R, Harris SA, Wolf DE, Hoffhine CE, Easton, NR, Folkers K, et al. Hydrogenation of Compounds Containing Divalent Sulfur. J Am Chem Soc 1945; 67: 2092-5, Hailu H , Atsbeha B, Admassie S, Mammo W, Raju VJT, Chebude Y, et al. Variable denticity of a multidentate terthiophene derivative towards ni (ii) and zn (ii) structural studies. Bull Chem Soc Ethiop 2011; 25: 221-31 ] To a solution of exothermic H2SO4 (110 mL),Exothermic HNO3 (60 mL) and concentratedH2SO4 (73 mL) was mixed in a flask,Cooled in an ice bath.2,5-dibromothiophene 4(2,5-dibromothiophene, 21.54 g, 89 mmol) was added dropwise and the temperature was maintained at 20-30 ° C. The reaction was stirred in ice for 4 h. The solid residue was filtered and washed with water and then purified by column chromatography (ethyl acetate in 20% hexane) to obtain light yellow powder (25.94 g, 88%).

References:

KR2018/17709,2018,A Location in patent:Paragraph 0173; 0176; 0180-0182

188290-36-0 Synthesis