ChemicalBook CAS DataBase List 2,5-DIBROMOBIPHENYL

2,5-DIBROMOBIPHENYL synthesis

10synthesis methods

Product Name:2,5-DIBROMOBIPHENYL
CAS Number:57422-77-2
Molecular formula:C12H8Br2
Molecular Weight:312

89284-52-6
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$6.00/1g

98-80-6 Synthesis

98-80-6
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$5.00/5g

57422-77-2
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$505.26/5MG

Yield: 98%

Reaction Conditions:

with tetrakis(triphenylphosphine) palladium⁽⁰⁾;potassium carbonate in tetrahydrofuran;water at 70 - 90;Inert atmosphere;

Steps:

(1) Under the protection of nitrogen, 0.1 mol 2,5-dibromoiodobenzene, 0.1 mol phenylboronic acid, and 100 ml tetrahydrofuran (THF) were added into a 250 ml reaction flask. Then, 0.001 mol Pd(PPh₃)₄and 20 ml of an aqueous 2M potassium carbonate solution were added to the reaction system. The reaction system was reacted at 70° C. to 90° C. for 10 to 24 h and cooled to room temperature naturally. The reaction solution was filtered. The filtrate was subjected to rotary evaporation under reduced pressure, and passed through a neutral silica gel column to obtain 2,5-dibromobiphenyl, with a HPLC purity of 99.25% and a yield of 98.0%.

References:

JIANGSU SUNERA TECHNOLOGY CO., LTD. US2021/163411, 2021, A1 Location in patent:Paragraph 0050-0051