ChemicalBook CAS DataBase List 4,4'-Dibromobiphenyl

4,4'-Dibromobiphenyl synthesis

15synthesis methods

Product Name:4,4'-Dibromobiphenyl
CAS Number:92-86-4
Molecular formula:C12H8Br2
Molecular Weight:312

5467-74-3
451 suppliers
$8.00/1g

92-86-4
383 suppliers
$15.00/25g

Yield:92-86-4 97%

Reaction Conditions:

with Cu₂(ophen)₂ in N,N-dimethyl-formamide at 20; for 20 h;

Steps:

4.3. Catalytic tests: general procedure I for the Cu2(ophen)2catalyzed homocoupling for Table 2

General procedure: 4.3. Catalytic tests: general procedure I for the Cu2(ophen)2catalyzed homocoupling for Table 2 A solution of the corresponding arylboronic acids (1.0 mmol),Cu2(ophen)2 (1.3 mg, 0.5 mol %), DMF (1.0 mL) in 5 mL round-bottomed ask was stirred under air and the reaction was moni-tored by TLC. After the substrate was consumed, the reaction con-versions were determined bygas chromatography (GC) analysis (FIDfrom AGILENT 7820) using a cross-linked (95%)-dimethyl-(5%)-diphenylpolysil-oxane column (HP-5, 30 m0.32 mm0.25 mm),helium, injector temperature 250 C, detector temperature 300 C,and oven temperature program 45 C (3 min)e20C/mine280 C(2 min). The resulting mixture was poured into brine (10 mL), andextracted with diethyl ether (310 mL). The organic layer waswashed with brine, dried over Mg2SO4, the residue was chromato-graphed via a short column of silica gel (petroleum ether: diethylether15:1) and evaporated under reduced pressure. The productswas determined by 1H NMR spectroscopy. All 1H NMR spectra weremeasured in CDCl3 with TMS as the internal standard.

References:

Wang, Yan-Hong;Xu, Mei-Chen;Liu, Jie;Zhang, Ling-Juan;Zhang, Xian-Ming [Tetrahedron,2015,vol. 71,# 52,p. 9598 - 9601]

92-52-4 Synthesis