2,6-DICHLOROPHENETHYLALCOHOL synthesis
- Product Name:2,6-DICHLOROPHENETHYLALCOHOL
- CAS Number:30595-79-0
- Molecular formula:C8H8Cl2O
- Molecular Weight:191.05
54551-83-6
97 suppliers
$30.00/1g
30595-79-0
141 suppliers
$8.00/250mg
Yield:-
Reaction Conditions:
with sodium tetrahydroborate in tetrahydrofuran;water at 5 - 10; for 4 h;
Steps:
1
2,6-Dichloro phenyl acetic acid methyl ester (1 eq) was taken in THF: Water (10:0.1(v/v) and cooled to 5-10 0C. NaBH4 was added to this mixture and mixture was stirred for 4 h. Mixture was quenched in water and extracted with EtOAc. Organic layer was washed with brine and evaporated in vacuo to afford title compound as thick liquid.
References:
CADILA HEALTHCARE LIMITED WO2009/87649, 2009, A1 Location in patent:Page/Page column 23
6575-24-2
290 suppliers
$8.00/5g
30595-79-0
141 suppliers
$8.00/250mg