![](/CAS/GIF/4214-75-9.gif)
2-Amino-3-nitropyridine synthesis
- Product Name:2-Amino-3-nitropyridine
- CAS Number:4214-75-9
- Molecular formula:C5H5N3O2
- Molecular Weight:139.11
![2-Chloro-3-nitropyridine](/CAS/GIF/5470-18-8.gif)
5470-18-8
432 suppliers
$6.00/5g
![2-Amino-3-nitropyridine](/CAS/GIF/4214-75-9.gif)
4214-75-9
403 suppliers
$9.00/5g
Yield:4214-75-9 97%
Reaction Conditions:
with ammonium hydroxide at 90; for 16 h;Sealed tube;
Steps:
1 3-Nitropyridin-2-amine (1):
3-Nitropyridin-2-amine (1): 2-chloro-3-nitropyridine (4 g, 25.23 mmol) was taken in a sealed tube and aqueous NH3 (8.57 g, 504.6 mmol) was added. The reaction mixture was heated to 90 °C and stirred for 16 h. The reaction mass was then cooled to 0 °C and filtered to obtain 1 (3.4 g, 97%) as a yellow solid. 1HNMR (400 MHz, DMSO-d6): δ 6.74 (m, 1H), 7.87 (s, 2H), 8.38 (m, 2H). MS m/z (M+H): 140.3
References:
CELGENE AVILOMICS RESEARCH, INC.;ALEXANDER, Matthew David;MCDONALD, Joseph John;NI, Yike;NIU, Deqiang;PETTER, Russell C.;QIAO, Lixin;SINGH, Juswinder;WANG, Tao;ZHU, Zhendong WO2014/149164, 2014, A1 Location in patent:Paragraph 001189
![2-Fluoro-3-nitropyridine](/CAS/GIF/1480-87-1.gif)
1480-87-1
203 suppliers
$6.00/1g
![2-Amino-3-nitropyridine](/CAS/GIF/4214-75-9.gif)
4214-75-9
403 suppliers
$9.00/5g
![2-Methoxy-3-nitropyridine](/CAS/GIF/20265-35-4.gif)
20265-35-4
201 suppliers
$22.00/1g
![2-Amino-3-nitropyridine](/CAS/GIF/4214-75-9.gif)
4214-75-9
403 suppliers
$9.00/5g
![3-Nitropyridine](/CAS/GIF/2530-26-9.gif)
2530-26-9
92 suppliers
$29.69/1g
![2-Amino-5-nitropyridine](/CAS/GIF/4214-76-0.gif)
4214-76-0
510 suppliers
$6.00/10g
![2-Amino-3-nitropyridine](/CAS/GIF/4214-75-9.gif)
4214-75-9
403 suppliers
$9.00/5g
![4-Amino-3-nitropyridine](/CAS/GIF/1681-37-4.gif)
1681-37-4
330 suppliers
$5.00/1g