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2-amino-4-phenoxyphenol synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 70 percent / 70percent HNO3, gl. AcOH / 0.25 h / Ambient temperature
2: 92 percent / H2 / 10percent Pd/C / ethyl acetate / 1 h / 2280 Torr / Ambient temperature

References:

Cinque, Güendalina M.;Szajnman, Sergio H.;Zhong, Li;Docampo, Roberto;Schvartzapel, Andrea J.;Rodriguez, Juan B.;Gros, Eduardo G. [Journal of Medicinal Chemistry,1998,vol. 41,# 9,p. 1540 - 1554]