2-AMINO-4-(PYRROLIDINE-1-SULFONYL)-PHENOL synthesis

4synthesis methods

Product Name:2-AMINO-4-(PYRROLIDINE-1-SULFONYL)-PHENOL
CAS Number:726151-75-3
Molecular formula:C10H14N2O3S
Molecular Weight:242.29

722464-31-5 Synthesis

Phenol, 2-nitro-4-(1-pyrrolidinylsulfonyl)-

722464-31-5
4 suppliers
inquiry

2-AMINO-4-(PYRROLIDINE-1-SULFONYL)-PHENOL

726151-75-3
11 suppliers
inquiry

Yield:-

Reaction Conditions:

palladium-carbon in tetrahydrofuran;

Steps:

R.33.4 Production of 2-amino-4-(pyrrolidine-1-sulfonyl)phenol

Step 4 Production of 2-amino-4-(pyrrolidine-1-sulfonyl)phenol 2-Nitro-4-(pyrrolidine-1-sulfonyl)phenol (2.19 g) was dissolved in tetrahydrofuran (50 mL). 7.5% Palladium-carbon (0.2 g) was added to this solution and, under a hydrogen atmosphere, the mixture was stirred at room temperature for 4 hrs. The reaction mixture was filtered through celite, and the residue was washed with tetrahydrofuran. The filtrate and washing solution were combined and the mixture was concentrated under reduced pressure. The obtained residue was purified by silica gel chromatography (n-hexane-ethyl acetate=1:l) to give the title compound (1.5494 g) as a cream color solid.

References:

US2008/305169,2008,A1

1-[(4-methoxy-3-nitrophenyl)sulfonyl]pyrrolidine

823823-46-7
1 suppliers
inquiry

726151-75-3
11 suppliers
inquiry

References

91-23-6
12 suppliers
$10.00/1g

726151-75-3
11 suppliers
inquiry

References

22117-79-9 Synthesis

4-methoxy-3-nitrobenzenesulphonyl chloride

22117-79-9
38 suppliers
inquiry

726151-75-3
11 suppliers
inquiry

References