![](/CAS/GIF/5467-64-1.gif)
2-AMINOPHENOL-N,O-DIACETATE synthesis
- Product Name:2-AMINOPHENOL-N,O-DIACETATE
- CAS Number:5467-64-1
- Molecular formula:C10H11NO3
- Molecular Weight:193.2
![synthesis of 2-AMINOPHENOL-N,O-DIACETATE.png synthesis of 2-AMINOPHENOL-N,O-DIACETATE.png](/NewsImg/2022-11-25/6380498532587803455905591.jpg)
![Acetic anhydride](/CAS/20180808/GIF/108-24-7.gif)
108-24-7
5 suppliers
$14.00/250ML
![2-Aminophenol](/CAS/GIF/95-55-6.gif)
95-55-6
531 suppliers
$5.00/5G
![2-AMINOPHENOL-N,O-DIACETATE](/CAS/GIF/5467-64-1.gif)
5467-64-1
16 suppliers
$28.60/250mg
Yield:5467-64-1 99.1%
Reaction Conditions:
with sulfuric acid in methanol; for 4 h;Reflux;Large scale;Concentration;
Steps:
2.1 preparation of 2-acetamidophenyl acetate
Take 2-aminophenol (110kg),Acetic anhydride (225 kg),Methanol 410kg,11 liters of concentrated sulfuric acid,Reflux reaction 4h. After the reaction,Methanol recovery under reduced pressure,Cool to room temperature,To the reaction system was added saturated sodium bicarbonate solution was adjusted to pH9-10,410kg ethyl acetate extraction,Washed to neutral,Dried over anhydrous sodium sulfate,filter,The solvent was recovered under reduced pressure,Had a light yellow solid 191.5kg,Yield 99.1%.
References:
CN106995366,2017,A Location in patent:Paragraph 0016; 0018
![Acetic acid](/CAS/GIF/64-19-7.gif)
64-19-7
1540 suppliers
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![2-Aminophenol](/CAS/GIF/95-55-6.gif)
95-55-6
531 suppliers
$5.00/5G
![2-AMINOPHENOL-N,O-DIACETATE](/CAS/GIF/5467-64-1.gif)
5467-64-1
16 suppliers
$28.60/250mg
![Acetic acid](/CAS/GIF/64-19-7.gif)
64-19-7
1540 suppliers
$10.00/25ML
![Acetanilide](/CAS/GIF/103-84-4.gif)
103-84-4
342 suppliers
$12.00/100g
![2-AMINOPHENOL-N,O-DIACETATE](/CAS/GIF/5467-64-1.gif)
5467-64-1
16 suppliers
$28.60/250mg
![Acetic anhydride](/CAS/20180808/GIF/108-24-7.gif)
108-24-7
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$14.00/250ML
![2-Nitrophenol](/CAS/GIF/88-75-5.gif)
88-75-5
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$15.00/5mg
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5467-64-1
16 suppliers
$28.60/250mg
![Acetyl chloride](/CAS/GIF/75-36-5.gif)
75-36-5
560 suppliers
$17.92/100G
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614-80-2
293 suppliers
$5.00/10g
![2-AMINOPHENOL-N,O-DIACETATE](/CAS/GIF/5467-64-1.gif)
5467-64-1
16 suppliers
$28.60/250mg