2-Acetamidophenol
- CAS No.
- 614-80-2
- Chemical Name:
- 2-Acetamidophenol
- Synonyms
- NSC 398;NSC 3989;2-Acetamino;AKOS BBB/377;O AcetaMinophen;acetoaminophenol;O-ACETAMINOPHENOL;O-ACETAMIDOPHENOL;2-ACETAMIDOPHENOL;2-acetamido-pheno
- CBNumber:
- CB0342159
- Molecular Formula:
- C8H9NO2
- Molecular Weight:
- 151.16
- MDL Number:
- MFCD00002181
- MOL File:
- 614-80-2.mol
- MSDS File:
- SDS
Melting point | 205-210 °C(lit.) |
---|---|
Boiling point | 273.17°C (rough estimate) |
Density | 1.2023 (rough estimate) |
refractive index | 1.5810 (estimate) |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Powder |
pka | 9.35±0.35(Predicted) |
color | Off-white to beige to brown |
BRN | 607592 |
Stability | Stable. Incompatible with strong oxidizing agents, chloroformates, acids, acid chlorides, acid anhydrides. |
InChI | InChI=1S/C8H9NO2/c1-6(10)9-7-4-2-3-5-8(7)11/h2-5,11H,1H3,(H,9,10) |
InChIKey | ADVGKWPZRIDURE-UHFFFAOYSA-N |
SMILES | C(NC1=CC=CC=C1O)(=O)C |
CAS DataBase Reference | 614-80-2(CAS DataBase Reference) |
EWG's Food Scores | 1 |
FDA UNII | 4AS8989RNI |
NIST Chemistry Reference | Acetamide, N-(2-hydroxyphenyl)-(614-80-2) |
EPA Substance Registry System | 2'-Hydroxyacetanilide (614-80-2) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Signal word | Warning | |||||||||
Hazard statements | H315-H319-H335 | |||||||||
Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
Hazard Codes | Xi,Xn | |||||||||
Risk Statements | 36/38-22-36/37/38 | |||||||||
Safety Statements | 26-36-37/39 | |||||||||
RIDADR | 2811 | |||||||||
WGK Germany | 3 | |||||||||
RTECS | AE4025000 | |||||||||
F | 1-8 | |||||||||
TSCA | Yes | |||||||||
HazardClass | 6.1(b) | |||||||||
PackingGroup | III | |||||||||
HS Code | 29242995 | |||||||||
NFPA 704 |
|
2-Acetamidophenol price More Price(33)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | A7000 | 2-Acetamidophenol 97% | 614-80-2 | 25g | $48.7 | 2024-03-01 | Buy |
Sigma-Aldrich | A7000 | 2-Acetamidophenol 97% | 614-80-2 | 100g | $90.1 | 2024-03-01 | Buy |
Sigma-Aldrich | 1003031 | Acetaminophen Related Compound C United States Pharmacopeia (USP) Reference Standard | 614-80-2 | 50mg | $1380 | 2024-03-01 | Buy |
TCI Chemical | H0189 | 2'-Hydroxyacetanilide >99.0%(HPLC)(N) | 614-80-2 | 25g | $68 | 2024-03-01 | Buy |
Alfa Aesar | B21264 | 2-Acetamidophenol, 97% | 614-80-2 | 25g | $22.65 | 2024-03-01 | Buy |
2-Acetamidophenol Chemical Properties,Uses,Production
Chemical Properties
white or light brown powder.soluble in hot water and ethanol, slightly soluble in cold water.
Uses
An Acetaminophen (A161220) impurity.
2-Acetamidophenol is used as raw material to manufacture industrial organic chemicals.
Acetaminophen is an analgesic and antipyretic agent and used as a pain reliever to treat headache, muscle aches, and arthritis.
Preparation
Mix 2-Aminophenol , acetic acid and Acetic anhydride (i.e., crystals appear), and then directly heated on the fire until all dissolved, stop heating, cooling, water dilution, precipitation of crystals filtered dry, to 70-80 ℃ of ethanol recrystallization to obtain 2-acetamidophenol.
Definition
ChEBI: 2-acetamidophenol is a member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties. It has a role as a platelet aggregation inhibitor, an anti-inflammatory agent, a xenobiotic metabolite, an apoptosis inducer, an antineoplastic agent and an antirheumatic drug. It is a member of phenols and a member of acetamides.
General Description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Purification Methods
Recrystallise it from water, EtOH or Est aqueous EtOH. [Beilstein 13 H 370, 13 I 113, 13 II 171, 13 III 778.]
2-Acetamidophenol Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD | +8618291886785 | olivia.wang@pushanshiye.com | China | 164 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12450 | 58 |
Apeloa production Co.,Limited | +8619933239880 | admin@apcl.com.cn | China | 853 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29894 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 | sales@sdzschem.com | China | 2931 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8822 | 58 |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from 2-Acetamidophenol manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
![]() |
2024-08-23 | acetoaminophenol
614-80-2
|
US $1.00 / g | 1g | 0.98 | 1000 | Apeloa production Co.,Limited | |
![]() |
2024-07-26 | 2-Acetamidophenol
614-80-2
|
US $0.00 / kg | 1kg | 98% | 2-5 MTs | PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD | |
![]() |
2023-09-06 | 2-Acetamidophenol
614-80-2
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. |
-
- acetoaminophenol
614-80-2
- US $1.00 / g
- 0.98
- Apeloa production Co.,Limited
-
- 2-Acetamidophenol
614-80-2
- US $0.00 / kg
- 98%
- PUSHAN INDUSTRIAL (SHAANXI) CO.,LTD
-
- 2-Acetamidophenol
614-80-2
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.