2-ANILINOACETAMIDE synthesis

11synthesis methods

Product Name:2-ANILINOACETAMIDE
CAS Number:21969-70-0
Molecular formula:C8H10N2O
Molecular Weight:150.18

62-53-3 Synthesis

62-53-3
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$10.00/1g

79-07-2
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$5.00/25g

21969-70-0
31 suppliers
$125.00/500mg

Yield:-

Reaction Conditions:

with potassium carbonate;potassium iodide in water;acetonitrile at 20;

Steps:

193a

EXAMPLE 193a Preparation of intermediate 2-phenylamino-acetamide The mixture of 2-chloroacetamide (3.1 g), aniline (3.1 g), K₂CO₃ (4.5 g) and KI (1 g) in acetonitrile (50 mL) and water (10 mL) was stirred at room temperature for overnight. The solvent was evaporated to about 20 ml under vacuum and the residue was poured into water (40 mL). The solution was extracted with ethyl acetate (3*20 mL), dried over Na₂SO₄ and concentrated. The residue was purified with chromatography to give 0.48 g of 2-phenylamino-acetamide.

References:

US2008/81810,2008,A1 Location in patent:Page/Page column 63

3009-97-0 Synthesis