![](/CAS/GIF/5394-13-8.gif)
2-BROMOBENZO[B]THIOPHENE synthesis
- Product Name:2-BROMOBENZO[B]THIOPHENE
- CAS Number:5394-13-8
- Molecular formula:C8H5BrS
- Molecular Weight:213.1
![Thianaphthene](/CAS/GIF/95-15-8.gif)
95-15-8
370 suppliers
$6.00/5g
![2-BROMOBENZO[B]THIOPHENE](/CAS/GIF/5394-13-8.gif)
5394-13-8
116 suppliers
$26.00/1g
Yield:5394-13-8 81%
Reaction Conditions:
Stage #1:Benzo[b]thiophene with sodium 2,2,6,6-tetramethylpiperidide in hexane at 25; for 0.5 h;
Stage #2: with 1,1,2,2-tetrabromoethane in hexane at -78; for 1 h;
Steps:
8.7 Experiment Number 7
General procedure: Benzo[b]thiophene was used as an arene, and 1,1,2,2-tetrabromoethane (Br2HCCHBr2) was used as an electrophilic reagent. The arene was reacted with Na-TMP in the same manner as in Experiment Number 2, the electrophilic reagent was added thereto and reacted therewith at -78° C. for 1 hour, the product was then evaluated, and the yield of isolated 2-bromo-benzo[b]thiophene in which a bromo group (-Br) was added at 2-position of benzo[b]thiophene was calculated. The isolated yield was 81%.
References:
KOBELCO ECO-SOLUTIONS CO.,LTD.;MURAKAMI, Yoshiaki;FUKUSHIMA, Miyuki;TAKAI, Kazuhiko;ASAKO, Sobi US2019/359571, 2019, A1 Location in patent:Paragraph 0127; 0130; 0131; 0140; 0141
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![2-BROMOBENZO[B]THIOPHENE](/CAS/GIF/5394-13-8.gif)
5394-13-8
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$26.00/1g
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![2-BROMOBENZO[B]THIOPHENE](/CAS/GIF/5394-13-8.gif)
5394-13-8
116 suppliers
$26.00/1g
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67-56-1
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201230-82-2
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$26.00/1g
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![2-BROMOBENZO[B]THIOPHENE](/CAS/GIF/5394-13-8.gif)
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116 suppliers
$26.00/1g
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6287-82-7
90 suppliers
$9.00/250mg