![](/CAS/GIF/109-04-6.gif)
2-Bromopyridine synthesis
- Product Name:2-Bromopyridine
- CAS Number:109-04-6
- Molecular formula:C5H4BrN
- Molecular Weight:158
![2-Aminopyridine](/CAS/GIF/504-29-0.gif)
504-29-0
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$5.00/5G
![2-Bromopyridine](/CAS/GIF/109-04-6.gif)
109-04-6
522 suppliers
$6.00/25g
Yield:109-04-6 91%
Reaction Conditions:
with 2-methylphenyl bromide;copper(I) bromide in cyclohexane at 5 - 45; for 3.41667 h;Concentration;Temperature;
Steps:
3 Example 3
(3) 1.9mol, reducing the solution temperature to 5 , control the stirring speed 170rpm, adding 1.5mol of cuprous bromide, the mass fraction is 55%, the reaction temperature is 5min, Cyclohexane 600ml, reaction 120min, the temperature increased to 45 , continue reaction 80min, adding the mass fraction of 35% sodium sulfite solution 300ml, reduce the solution temperature to 35 , 50min reaction, the solution with 65% acetonitrile extraction 5 times , The combined acetonitrile extract, potassium nitrate solution washing, anhydrous potassium carbonate dehydration, recovery of acetonitrile, 1.9kPa vacuum distillation, 90-95 ° C fractions collected 90% ethylenediamine in the mass fraction recrystallization, was 186.91 g of 2-bromopyridine was obtained in 91% yield.
References:
CN105439944,2016,A Location in patent:Paragraph 0015; 0016
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109-04-6
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$6.00/25g
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109-04-6
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![2-Bromopyridine](/CAS/GIF/109-04-6.gif)
109-04-6
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$6.00/25g
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626-05-1
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![2-Bromopyridine](/CAS/GIF/109-04-6.gif)
109-04-6
522 suppliers
$6.00/25g