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ChemicalBook CAS DataBase List 2-CHLORO-3-PHENYLQUINOLINE

2-CHLORO-3-PHENYLQUINOLINE synthesis

14synthesis methods
-

Yield:2859-30-5 97%

Reaction Conditions:

Stage #1: N-<2-(2-Phenylethynyl)phenyl>methanamidewith N-ethyl-N,N-diisopropylamine;trichlorophosphate in dichloromethane at 0; for 1 h;Inert atmosphere;
Stage #2: with tetrabutyl-ammonium chloride in dichloromethane at 40; for 15 h;Inert atmosphere;

References:

Liu, Lanying;Wang, Yong;Wang, Honggen;Peng, Changlan;Zhao, Jiaji;Zhu, Qiang [Tetrahedron Letters,2009,vol. 50,# 48,p. 6715 - 6719] Location in patent:experimental part

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