![](/CAS/GIF/23056-39-5.gif)
2-Chloro-4-methyl-3-nitropyridine synthesis
- Product Name:2-Chloro-4-methyl-3-nitropyridine
- CAS Number:23056-39-5
- Molecular formula:C6H5ClN2O2
- Molecular Weight:172.57
![2-Hydroxy-4-methyl-3-nitropyridine](/CAS/GIF/21901-18-8.gif)
21901-18-8
235 suppliers
$25.00/5g
![2-Chloro-4-methyl-3-nitropyridine](/CAS/GIF/23056-39-5.gif)
23056-39-5
324 suppliers
$6.00/1g
Yield:23056-39-5 75.3%
Reaction Conditions:
with trichlorophosphate for 4 h;Reflux;
Steps:
1
Synthesis of the compound 10 The compound 9 (13g, 0.084mol) was added into 50mL of phosphorus oxychloride, the mixture was heated under reflux for 4 h, and distilled to remove excessive phosphorus oxychloride. The resulted product was recrystallized in 50mL of ethanol (75%) to yield 11 g of a white solid product with yield of 75.3%. The melting point: 51.7-52.1 °C(ethanol) (M.P. 52.0-52.9 °C was reported in reference)[J.O.C., 1955, 20, 1729-1731].
References:
Beijing Yiling Bioengineering Co., Ltd. EP2366691, 2011, A1 Location in patent:Page/Page column 7
![2-Hydroxy-4-methyl-3-nitropyridine](/CAS/GIF/21901-18-8.gif)
21901-18-8
235 suppliers
$25.00/5g
![2-Chloro-4-methyl-3-nitropyridine](/CAS/GIF/23056-39-5.gif)
23056-39-5
324 suppliers
$6.00/1g
![2-Amino-3-nitro-4-picoline](/CAS/GIF/6635-86-5.gif)
6635-86-5
303 suppliers
$10.00/5g
![2-Chloro-4-methyl-3-nitropyridine](/CAS/GIF/23056-39-5.gif)
23056-39-5
324 suppliers
$6.00/1g
![4-Methylpyridin-2-amine](/CAS/GIF/695-34-1.gif)
695-34-1
521 suppliers
$5.00/10g
![2-Chloro-4-methyl-5-nitropyridine](/CAS/GIF/23056-33-9.gif)
23056-33-9
329 suppliers
$3.00/1g
![2-Chloro-4-methyl-3-nitropyridine](/CAS/GIF/23056-39-5.gif)
23056-39-5
324 suppliers
$6.00/1g
![4-Methylpyridin-2-amine](/CAS/GIF/695-34-1.gif)
695-34-1
521 suppliers
$5.00/10g
![2-Chloro-4-methyl-3-nitropyridine](/CAS/GIF/23056-39-5.gif)
23056-39-5
324 suppliers
$6.00/1g