![](/CAS/GIF/118-91-2.gif)
2-Chlorobenzoic acid synthesis
- Product Name:2-Chlorobenzoic acid
- CAS Number:118-91-2
- Molecular formula:C7H5ClO2
- Molecular Weight:156.57
The chloride is readily replaced by ammonia to 2-aminobenzoic acid. At elevated temperature it decarboxylates.
![2-Chlorobenzonitrile](/CAS/GIF/873-32-5.gif)
873-32-5
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![2-Chlorobenzoic acid](/CAS/GIF/118-91-2.gif)
118-91-2
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$14.00/25g
Yield:118-91-2 168 g
Reaction Conditions:
with hydrogenchloride in water monomer at 100 - 110;
Steps:
10 Example 10: Preparation of ortho-chloro benzoic acid (IV)
To a mixture of ortho-chloro benzonitrile (250 g) and water (562.5 g), concentrated hydrochloric acid (187.5 g) was added under stirring for 15 to 30 minutes and mixture was heated to 100°C to 110°C for 6 to 8 hours. The reaction mixture was cooled to room temperature and stirred for 1 to 2 hours. The precipitated solid was filtered, washed with water and dried under vacuum to get ortho-chloro benzoic acid compound (168 g, 98%, HPLC purity 99.79%).
References:
WO2022/91014,2022,A1 Location in patent:Page/Page column 12
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2142-68-9
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![2-Chlorobenzoic acid](/CAS/GIF/118-91-2.gif)
118-91-2
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![2-Chlorostyrene](/CAS/GIF/2039-87-4.gif)
2039-87-4
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![2-Chlorobenzoic acid](/CAS/GIF/118-91-2.gif)
118-91-2
638 suppliers
$14.00/25g