ChemicalBook CAS DataBase List 2-CYCLOPENTYL-5-METHYL-2H-PYRAZOL-3-YLAMINE

2-CYCLOPENTYL-5-METHYL-2H-PYRAZOL-3-YLAMINE synthesis

5synthesis methods

Product Name:2-CYCLOPENTYL-5-METHYL-2H-PYRAZOL-3-YLAMINE
CAS Number:30241-37-3
Molecular formula:C9H15N3
Molecular Weight:165.24

2469-99-0
90 suppliers
$16.00/1g

30923-92-3
22 suppliers
$98.00/5g

2-CYCLOPENTYL-5-METHYL-2H-PYRAZOL-3-YLAMINE

30241-37-3
22 suppliers
$46.00/1g

Yield:-

Reaction Conditions:

with acetic acid in ethanol;Reflux;

Steps:

1-cyclohexyl-3-methyl-1H-pyrazol-5-amine.

General procedure: In a 250 mL RBF, 3-aminobut-2-enenitrile (2.0 g, 0.24 mole) was added to a stirred solution of cyclohexyl hydrazine hydrochloride (4.0 g, 0.026 mole) and acetic acid (0.1 mL) in ethanol (60 mL). The reaction was refluxed for 6 h. Crude was evaporated and loaded on column to elute out product at 40% ethyl acetate in hexane. (1.74 g, 40%)

References:

Sharma, Swagat;Kozek, Krystian A.;Abney, Kristopher K.;Kumar, Sushil;Gautam, Nagsen;Alnouti, Yazen;David Weaver;Hopkins, Corey R. [Bioorganic and Medicinal Chemistry Letters,2019,vol. 29,# 6,p. 791 - 796] Location in patent:supporting information

1118-61-2 Synthesis