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1269515-03-8

2-Hydroxy-4-phenethylisoquinoline-1,3(2H,4H)-dione synthesis

3synthesis methods
1269514-88-6 Synthesis
2-(Benzyloxy)-4-phenethylisoquinoline-1,3(2H,4H)-dione

1269514-88-6
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2-Hydroxy-4-phenethylisoquinoline-1,3(2H,4H)-dione

1269515-03-8
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Yield:1269515-03-8 70%

Reaction Conditions:

Stage #1: 2-benzyloxy-4-(2-phenyl)ethylisoquinoline-1,3(2H,4H)-dione at 20; for 1 h;
Stage #2: with water at 20; for 0.25 h;

References:

Billamboz, Muriel;Bailly, Fabrice;Lion, Cedric;Calmels, Christina;Andreola, Marie-Line;Witvrouw, Myriam;Christ, Frauke;Debyser, Zeger;De Luca, Laura;Chimirri, Alba;Cotelle, Philippe [European Journal of Medicinal Chemistry,2011,vol. 46,# 2,p. 535 - 546] Location in patent:scheme or table