2-Mercaptopropionic acid synthesis

Yield:79-42-5 95 g

Reaction Conditions:

with Lawessons reagent in toluene at 80; for 12 h;Reagent/catalyst;

Steps:

4 Example 4
110 g of 2-hydroxypropionic acid potassium salt was added to 2000 mL of toluene in a reaction flask, and 400 g of Lawson reagent was added,After heating to 80 ° C for 12 h, the reaction mixture was concentrated and the concentrate was poured into ice water. The pH of the solution was adjusted with dilute hydrochloric acid4 and extracted with ethyl acetate to give 95 g of 2-mercaptopropionic acid.

References:

Henan Normal University;Xu, Guiqing;Jiang, Yuqin;Mao, Longfei;Li, Wei;Zhang, Dandan;Zhang, Yingui;Li, Xing;Mu, Kairui;Cao, Xiaohui CN106146365, 2016, A Location in patent:Paragraph 0032; 0033; 0034; 0035

FullText