![](/CAS/GIF/2637-34-5.gif)
2-Pyridinethione synthesis
- Product Name:2-Pyridinethione
- CAS Number:2637-34-5
- Molecular formula:C5H5NS
- Molecular Weight:111.16
![2-Iodopyridine](/CAS/GIF/5029-67-4.gif)
5029-67-4
292 suppliers
$6.00/1g
![2-Pyridinethione](/CAS/GIF/2637-34-5.gif)
2637-34-5
309 suppliers
$6.00/5g
Yield:2637-34-5 76%
Reaction Conditions:
with sodiumsulfide nonahydrate;copper;ethane-1,2-dithiol in dimethyl sulfoxide at 100; for 20 h;Inert atmosphere;Green chemistry;
Steps:
General Experimental Procedure for the Synthesis of ArylThiols from Aryl Iodides
General procedure: To a test tube containing a magnetic bar was added aryl iodide(1 mmol), copper powder (6.35 mg, 0.1 mmol), Na2S·9H2O(720.54 mg, 3 mmol), and DMSO (2 mL). After flushing withargon, 1,2-ethanedithiol (8.4 μL, 0.1 mmol) was added. Themixture was stirred in the oil bath at 100 °C for 20 h. Aftercooled to ambient temperature, the reaction mixture was distributedin aq HCl (5%) and EtOAc. The organic layer was separated and washed with water and brine, dried, and concentratedunder vacuum. The crude product was further purifiedby column chromatography using ethyl acetate/n-hexane aseluent to provide the desired aryl thiol.
References:
Xue, Hongyu;Jing, Bing;Liu, Shasha;Chae, Junghyun;Liu, Yajun [Synlett,2017,vol. 28,# 17,art. no. ST-2017-W0384-L,p. 2272 - 2276]
![2-Pyridinethiol 1-oxide](/CAS/GIF/1121-31-9.gif)
1121-31-9
173 suppliers
$16.00/5g
![2-Pyridinethione](/CAS/GIF/2637-34-5.gif)
2637-34-5
309 suppliers
$6.00/5g
![2,2'-Dithiodipyridine](/CAS/GIF/2127-03-9.gif)
2127-03-9
249 suppliers
$10.00/1g
![2-Pyridinethione](/CAS/GIF/2637-34-5.gif)
2637-34-5
309 suppliers
$6.00/5g
![2-Bromopyridine](/CAS/GIF/109-04-6.gif)
109-04-6
523 suppliers
$6.00/25g
![2-Pyridinethione](/CAS/GIF/2637-34-5.gif)
2637-34-5
309 suppliers
$6.00/5g
![L-Leucine](/CAS/GIF/61-90-5.gif)
61-90-5
779 suppliers
$10.00/25G
![Carbonothioic acid, O-(1,1-dimethylethyl) S-2-pyridinyl ester (9CI)](/CAS/20210305/GIF/105678-24-8.gif)
105678-24-8
0 suppliers
inquiry
![2-Pyridinethione](/CAS/GIF/2637-34-5.gif)
2637-34-5
309 suppliers
$6.00/5g
![BOC-L-Leucine](/CAS/GIF/13139-15-6.gif)
13139-15-6
429 suppliers
$7.00/5g