ChemicalBook CAS DataBase List 2-Methyl-1,3-dioxolane-2-ethanol

2-Methyl-1,3-dioxolane-2-ethanol synthesis

7synthesis methods

Product Name:2-Methyl-1,3-dioxolane-2-ethanol
CAS Number:5754-32-5
Molecular formula:C6H12O3
Molecular Weight:132.16

6413-10-1
237 suppliers
$10.00/5g

7757-82-6 Synthesis

7757-82-6
778 suppliers
$6.00/5g

5754-32-5
48 suppliers
$32.00/100mg

Yield: 97%

Reaction Conditions:

in diethyl ether

Steps:

1 EXAMPLE 1
Lithium aluminium hydride (2 g, 51 mmol) is added in small portions to anhydrous ethyl ether (200 cc). The mixture is cooled to 0° C. and ethyl 3,3-ethylenedioxybutanoate (3 g, 17 mmol) is then added over 10 minutes as a solution in anhydrous ethyl ether (10 cc). The mixture is stirred for 2 hours 30 minutes at a temperature in the region of 20° C. and is then hydrolyzed by adding a saturated sodium sulphate solution (12 cc). After 2 hours the white precipitate is separated off by filtration. The organic phases are dried over magnesium sulphate. 2,2-Ethylenedioxy-4-hydroxybutane (2.22 g) is thus obtained. The yield is 97%. Ethyl 3,3-ethylenedioxybutanoate can be prepared as follows:

References:

Rhone-Poulenc Sante US4876370, 1989, A

6413-10-1
237 suppliers
$10.00/5g

5754-32-5
48 suppliers
$32.00/100mg

References