ChemicalBook CAS DataBase List 2-Methyl-5-pyrimidinemethanol

2-Methyl-5-pyrimidinemethanol synthesis

3synthesis methods

Product Name:2-Methyl-5-pyrimidinemethanol
CAS Number:2239-83-0
Molecular formula:C6H8N2O
Molecular Weight:124.14

5194-32-1
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$21.89/250mg

2239-83-0
136 suppliers
$21.00/250mg

Yield: 62.6%

Reaction Conditions:

with sodium tetrahydroborate;ethanol at 20; for 3 h;

Steps:

24.1 Step 1 (2-methylpyrimidin-5-yl)methanol
Step 1 (2-methylpyrimidin-5-yl)methanol To a solution of 2-methylpyrimidine-5-carboxylic acid (150 mg, 1.23 mmOl) in ethanol (5 mL) was added sodium borohydride(93 mg, 2.46 mmol). The mixture was stirred at room temperature for 3 h. It was quenched with aqueous HC1 (2 N, 2 mL), extracted with DCM, dried over sodium sulfate, filtered and concentrated give the yellow oil product (2-methylpyrimidin-5-yl)methanol (95 mg, 62.6%). LCMS MH⁺ 125.

References:

HYDRA BIOSCIENCES, INC.;CHENARD, Bertrand;GALLASCHUN, Randall WO2014/143799, 2014, A2 Location in patent:Page/Page column 387

90905-33-2
131 suppliers
$38.00/500mg

2239-83-0
136 suppliers
$21.00/250mg

References

Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

1000210-73-0
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2239-83-0
136 suppliers
$21.00/250mg

References

2-Methyl-5-pyrimidinemethanol Related Search:

2-Methylpyrimidine Methylparaben Methyl acetate 5-Fluorouracil Pirimiphos-methyl 2,6-Lutidine Parathion-methyl 5-Pyrimidinemethanol ETHYL-2,4-DIMETHYL-5-PYRIMIDINE CARBOXYLATE ethyl 4-hydroxy-2-(2-pyridinyl)-5-pyrimidinecarboxylate