ChemicalBook CAS DataBase List 2-Methylcyclopentanone

2-Methylcyclopentanone synthesis

12synthesis methods

Product Name:2-Methylcyclopentanone
CAS Number:1120-72-5
Molecular formula:C6H10O
Molecular Weight:98.14

methyl 1-methyl-2-oxocyclopentanecarboxylate

30680-84-3
29 suppliers
$106.00/5MG

1120-72-5
150 suppliers
$8.00/1g

Yield:1120-72-5 95%

Reaction Conditions:

with sulfuric acid in water at 100; for 10 h;

Steps:

2 Preparation of 2-methylcyclopentanone

Methyl 1-methyl-2-oxocyclopentanecarboxylate (200 g, 1.3 mol), water (1.5 L), concentrated sulfuric acid (7.5 mL, 0.13 mol),After the addition, the temperature was raised to 100 ° C for 10 hours.The system is cooled to room temperature,The organic phase was combined and washed with 5% sodium hydrogencarbonate and saturated brine.Drying over anhydrous sodium sulfate, distilling off the solvent and distilling under reduced pressure to give 2-methylcyclopentanone 120 g.The yield was 95%.

References:

CN110204500,2019,A Location in patent:Paragraph 0055-0057