2-methylpent-4-ynoic acid synthesis
- Product Name:2-methylpent-4-ynoic acid
- CAS Number:74064-82-7
- Molecular formula:C6H8O2
- Molecular Weight:112.13
Yield:74064-82-7 68%
Reaction Conditions:
Stage #1: propionic acidwith N,N,N,N,N,N-hexamethylphosphoric triamide;n-butyllithium;diisopropylamine in tetrahydrofuran;hexane at 20; for 1 h;
Stage #2: propargyl bromide in tetrahydrofuran;toluene at 20; for 16 h;
References:
Pettigrew, Jeremy D.;Freeman, Rebecca P.;Wilson, Peter D. [Canadian Journal of Chemistry,2004,vol. 82,# 11,p. 1640 - 1648]
4371-04-4
0 suppliers
inquiry
74064-82-7
5 suppliers
inquiry