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18162-48-6872-50-4Methylene ChloridenaphthaleneTHFTitanium Dioxide

2-(o-Tolyl)propanenitrile synthesis

13synthesis methods
22364-68-7 Synthesis
2-Methylbenzyl cyanide

22364-68-7
269 suppliers
$6.00/10g

Iodomethane

74-88-4
342 suppliers
$15.00/10g

2-(o-Tolyl)propanenitrile

58422-60-9
22 suppliers
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Yield:58422-60-9 94%

Reaction Conditions:

Stage #1: 2-tolylmethylnitrilewith potassium tert-butylate in tetrahydrofuran at -78; for 1 h;Inert atmosphere;
Stage #2: methyl iodide in tetrahydrofuran at -78 - 20; for 20 h;Inert atmosphere;

References:

Kodama, Koichi;Kanai, Hayato;Shimomura, Yuki;Hirose, Takuji [European Journal of Organic Chemistry,2018,vol. 2018,# 14,p. 1726 - 1729] Location in patent:supporting information

Benzene, 1-methyl-2-(trifluorosilyl)-

363-86-0
0 suppliers
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19481-82-4 Synthesis
2-BROMOPROPIONITRILE

19481-82-4
77 suppliers
$24.00/1g

2-(o-Tolyl)propanenitrile

58422-60-9
22 suppliers
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References
625-28-5 Synthesis
3-Methylbutanenitrile

625-28-5
85 suppliers
$82.00/5g

611-15-4 Synthesis
2-METHYLSTYRENE

611-15-4
114 suppliers
$139.00/1mL

2-(o-Tolyl)propanenitrile

58422-60-9
22 suppliers
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3-(2-methylphenyl)propanenitrile

26016-32-0
3 suppliers
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References
557-21-1 Synthesis
ZINC CYANIDE

557-21-1
98 suppliers
$12.00/5g

611-15-4 Synthesis
2-METHYLSTYRENE

611-15-4
114 suppliers
$139.00/1mL

2-(o-Tolyl)propanenitrile

58422-60-9
22 suppliers
inquiry

3-(2-methylphenyl)propanenitrile

26016-32-0
3 suppliers
inquiry

References
2-Trimethylsilanyl-propionitrile

18151-58-1
7 suppliers
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95-46-5 Synthesis
2-Bromotoluene

95-46-5
295 suppliers
$10.00/10g

2-(o-Tolyl)propanenitrile

58422-60-9
22 suppliers
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References