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2-Pentenoic acid, 2,4,4-trimethyl-, (2E)- synthesis

3synthesis methods
-

Yield:60065-21-6 21%

Reaction Conditions:

with manganese;(1,2-dimethoxyethane)dichloronickel(II);Bathocuproine;tert-butyl alcohol in N,N-dimethyl-formamide at 60; for 36 h;Schlenk technique;regioselective reaction;

References:

Wang, Xueqiang;Nakajima, Masaki;Martin, Ruben [Journal of the American Chemical Society,2015,vol. 137,# 28,p. 8924 - 8927] Location in patent:supporting information