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2-Phenyl-1-(phenylmethyl)-4-piperidinone synthesis

4synthesis methods
1-Penten-3-one, 1-phenyl-5-[(phenylmethyl)amino]-, (1E)-

824938-70-7
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2-Phenyl-1-(phenylmethyl)-4-piperidinone

167705-56-8
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Yield:167705-56-8 75%

Reaction Conditions:

with aluminum oxide;cerium(III) chloride;sodium iodide at 35; for 24 h;Michael addition;

References:

Bartoli, Giuseppe;Bartolacci, Massimo;Giuliani, Arianna;Marcantoni, Enrico;Massaccesi, Massimo;Torregiani, Elisabetta [Journal of Organic Chemistry,2005,vol. 70,# 1,p. 169 - 174]