2-PHENYLAMINO-TEREPHTHALIC ACID synthesis

10synthesis methods

Product Name:2-PHENYLAMINO-TEREPHTHALIC ACID
CAS Number:566155-75-7
Molecular formula:C14H11NO4
Molecular Weight:257.24

dimethyl 2-(phenylamino)benzene-1,4-dioate

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Yield:566155-75-7 99.3%

Reaction Conditions:

with lithium hydroxide monohydrate in ethanol at 20;

Steps:

1.4

hydrolysis of esters: The compound IV dissolved 10.5g 100ml 95% EtOH was added 7.7g LiOH · H₂O, stirred at room temperature overnight, the next day the detection, compound IV completely consumed, the solid was removed by filtration, the filtrate was evaporated to dryness, the residue dissolved in water, pH adjusted to about 3-4 with 1M HCl, the precipitated solid was filtered, filter cake Et₂O washing and drying give 9.4g 2- anilino-terephthalate (i.e., compound V ), as shown in FIG.4 yield 99.3%.

References:

CN104072403,2016,B Location in patent:Paragraph 0036