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2-Trifluoromethyl-1H-quinolin-4-one synthesis

4synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: LiH / tetrahydrofuran / 3 h / Heating
2.1: aq. HCl / ethanol / 6 h / Heating
2.2: 65 percent / H2O / 20 h / Heating

References:

Sosnovskikh;Usachev;Sizov [Russian Chemical Bulletin,2002,vol. 51,# 11,p. 2109 - 2115]