5-(TOSYLOXYIMINO)-2,2-DIMETHYL-1,3-DIOXANE-4,6-DIONE synthesis
1synthesis methods
- Product Name:5-(TOSYLOXYIMINO)-2,2-DIMETHYL-1,3-DIOXANE-4,6-DIONE
- CAS Number:215436-24-1
- Molecular formula:C13H13NO7S
- Molecular Weight:327.31
Yield:215436-24-1 59%
Reaction Conditions:
Stage #1: cycl-isopropylidene malonatewith sodium nitrite in methanol;water at 20; for 2 h;Inert atmosphere;
Stage #2: p-toluenesulfonyl chloride in methanol;aq. phosphate buffer;water at 0; pH=7; for 0.55 h;Inert atmosphere;
References:
Danheiser, Rick L.;Renslo, Adam R.;Amos, David T.;Wright, Graham T.;Krause, Helga;Fürstner, Alois [Organic Syntheses,2003,vol. 80,p. 133 - 143]