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ChemicalBook CAS DataBase List 3-(1H-BENZOIMIDAZOL-2-YL)-2-METHYL-PHENYLAMINE

3-(1H-BENZOIMIDAZOL-2-YL)-2-METHYL-PHENYLAMINE synthesis

4synthesis methods
1H-Benzimidazole, 2-(2-methyl-3-nitrophenyl)-

1254103-75-7
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Yield:428856-24-0 81%

Reaction Conditions:

with 10% palladium on activated carbon;hydrogen in methanol;ethanol;ethyl acetate at 20; for 3 h;

References:

Keurulainen, Leena;Salin, Olli;Siiskonen, Antti;Kern, Jan Marco;Alvesalo, Joni;Kiuru, Paula;Maass, Matthias;Yli-Kauhaluoma, Jari;Vuorela, Pia [Journal of Medicinal Chemistry,2010,vol. 53,# 21,p. 7664 - 7674] Location in patent:supporting information; experimental part