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3,3,4,4,5,5,5-HEPTAFLUORO-2-PENTANOL synthesis

6synthesis methods
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Yield:85571-83-1 12% ,355-17-9 43% ,375-86-0 8%

Reaction Conditions:

in further solvent(s);addition of the grignard solution to the ester (solution in n-butyl ether) at -50°C, stirring at -40°C, 24 hours, warming to 20°C within 24 hours and stirring for 24 hours;;

References:

Haszeldine, R. N. [Journal of the Chemical Society][Journal of the Chemical Society,1953,p. 1748 - 1757]