ChemicalBook CAS DataBase List 3,3-diphenylpropyl methyl ammonium chloride

3,3-diphenylpropyl methyl ammonium chloride synthesis

3synthesis methods

Product Name:3,3-diphenylpropyl methyl ammonium chloride
CAS Number:29768-15-8
Molecular formula:C16H20ClN
Molecular Weight:261.7897

42142-52-9 Synthesis

42142-52-9
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$11.00/25g

71-43-2
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$11.19/25ML

3,3-diphenylpropyl methyl ammonium chloride

29768-15-8
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Yield:29768-15-8 95 %

Reaction Conditions:

Stage #1: 3-methylamino-1-phenylpropan-1-ol;benzene in dichloromethane at 40 - 45;
Stage #2: with hydrogenchloride in ethanol;water;Reflux;

Steps:

3 Example 3: N-methyl-3,3-diphenylpropylamine hydrochloride

560g α-[2-(methylamino)ethyl]benzyl alcohol (0.85mol1.0eq) 25% dichloromethane solution and 280g benzene were pumped into the infusion pump mixer through the metering pump at 280g/min and 140g/min, respectively, and after full mixing, they entered the load with Re_2O7(411g1.0eq) catalyst micro-packed bed reactor, the reaction temperature is 40-45 °C, the reaction time is 2min, the reaction solution is obtained, dichloromethane is recovered under atmospheric pressure at 45 °C, benzene is recovered under reduced pressure at 60 °C, enter the application system, the concentrate is added to 5V2% hydrochloric acid (700mL) 1V ethanol (140mL), heated to reflux, stirred for 1h, fully dissolved, cooled to 0-5 °C, stirred for 2-3 hours, filtered and dried to obtain N-methyl-3,3- Diphenylpropylamine hydrochloride 210.7g, purity 99.8%, yield 95.0%.

References:

CN115677512,2023,A Location in patent:Paragraph 0023-0025

98-86-2 Synthesis

98-86-2
754 suppliers
$9.00/5g

29768-15-8
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References

Benzhydrol, α-[2-(benzylmethylamino)ethyl]- (8CI)

25772-95-6
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29768-15-8
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References