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ChemicalBook CAS DataBase List 3,4,5-Trifluoropyridine
67815-54-7

3,4,5-Trifluoropyridine synthesis

7synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 4 steps
1.1: 68 percent / hydrazine monohydrate / ethanol / 6 h / Heating
2.1: 79 percent / aq. CuSO4 / Heating
3.1: BuLi / tetrahydrofuran; hexane
3.2: 73 percent / hexachloroethane / tetrahydrofuran; hexane
4.1: 51 percent / KF; tetramethylammonium chloride / dimethylsulfoxide / 6 h / 150 °C

References:

Bobbio, Carla;Rausis, Thierry;Schlosser, Manfred [Chemistry - A European Journal,2005,vol. 11,# 6,p. 1903 - 1910]

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