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ChemicalBook CAS DataBase List 3-(4-chlorobutyl)-1-tosyl-1H-indole-5-carbonitrile

3-(4-chlorobutyl)-1-tosyl-1H-indole-5-carbonitrile synthesis

4synthesis methods
1H-Indole-5-carbonitrile, 3-(4-chloro-1-oxobutyl)-1-[(4-methylphenyl)sulfonyl]-

1398358-62-7
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3-(4-chlorobutyl)-1-tosyl-1H-indole-5-carbonitrile

1398358-69-4
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Yield:1398358-69-4 95%

Reaction Conditions:

with sodium tetrahydridoborate;trifluoroacetic acid in dichloromethane at 15 - 20; for 6 h;Large scale;

References:

Hu, Bin;Song, Qiao;Xu, Yungen [Organic Process Research and Development,2012,vol. 16,# 9,p. 1552 - 1557]