3-[4-(TrifluoroMethyl)phenyl]benzonitrile synthesis

7synthesis methods

Product Name:3-[4-(TrifluoroMethyl)phenyl]benzonitrile
CAS Number:893734-90-2
Molecular formula:C14H8F3N
Molecular Weight:247.22

873-62-1 Synthesis

873-62-1
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3-[4-(TrifluoroMethyl)phenyl]benzonitrile

893734-90-2
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Yield:-

Steps:

Multi-step reaction with 2 steps
1: triethylamine; dmap / dichloromethane / 16 h / 0 - 20 °C / Inert atmosphere
2: bis(triphenylphosphine)nickel(II) chloride / tetrahydrofuran / 5 h / 40 °C / Inert atmosphere; Schlenk technique

References:

Hofmayer, Maximilian S.;Lutter, Ferdinand H.;Grokenberger, Lucie;Hammann, Jeffrey M.;Knochel, Paul [Organic Letters,2019,vol. 21,# 1,p. 36 - 39]

1-Butanesulfonic acid, 1,1,2,2,3,3,4,4,4-nonafluoro-, 3-cyanophenyl ester

873838-45-0
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Zinc, chloro[4-(trifluoromethyl)phenyl]-

125102-17-2
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893734-90-2
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References

69113-59-3
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402-43-7 Synthesis

402-43-7
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893734-90-2
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References

6952-59-6 Synthesis

6952-59-6
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98-56-6 Synthesis

98-56-6
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$11.00/25g

893734-90-2
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References

6952-59-6 Synthesis

6952-59-6
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128796-39-4 Synthesis

128796-39-4
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893734-90-2
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References