![](/CAS/20180808/GIF/4179-19-5.gif)
3,5-Dimethoxytoluene synthesis
- Product Name:3,5-Dimethoxytoluene
- CAS Number:4179-19-5
- Molecular formula:C9H12O2
- Molecular Weight:152.19
![Orcinol](/CAS/GIF/504-15-4.gif)
504-15-4
379 suppliers
$7.00/100mg
![3,5-Dimethoxytoluene](/CAS/20180808/GIF/4179-19-5.gif)
4179-19-5
148 suppliers
$6.00/1g
Yield:4179-19-5 82%
Reaction Conditions:
with potassium carbonate;dimethyl sulfate in acetonitrile
Steps:
44 Example 44
Example 44 (Reference Example) 3,5-dimethoxy toluene Commercially available orcinol (5.77 g) was dissolved in acetonitrile (200 ml), dimethyl sulfate (8.47 ml) and potassium carbonate (12.3 g) were added, and the admixture was refluxed for 2.5 hours. The reaction mixture was poured into ice water and partitioned with chloroform, and the chloroform layer was dried with anhydrous magnesium sulfate. The solvent was removed by reduced-pressure distillation, and the resulting residue was purified by column chromatography on silica gel eluding with hexane/ethyl acetate (5/1) to obtain 5.04 g of the title compound (yield: 82%). 1 H-NMR (CDCl3, 500 MHz): δ 2.30 (s, 3H), 3.76 (s, 6H), 6.30 (s, 1H), 6.37 (s, 2H)
References:
Kirin Beer Kabushiki Kaisha US6143764, 2000, A
![3,5-Dimethoxybenzaldehyde](/CAS/GIF/7311-34-4.gif)
7311-34-4
318 suppliers
$10.00/1g
![3,5-Dimethoxytoluene](/CAS/20180808/GIF/4179-19-5.gif)
4179-19-5
148 suppliers
$6.00/1g
![Orcinol](/CAS/GIF/504-15-4.gif)
504-15-4
379 suppliers
$7.00/100mg
![Dimethyl sulfate](/CAS/GIF/77-78-1.gif)
77-78-1
290 suppliers
$19.69/1ml
![3,5-Dimethoxytoluene](/CAS/20180808/GIF/4179-19-5.gif)
4179-19-5
148 suppliers
$6.00/1g
![3,5-DIMETHOXYBENZYL BROMIDE](/CAS/20180808/GIF/877-88-3.gif)
877-88-3
228 suppliers
$5.00/250mg
![3,5-Dimethoxytoluene](/CAS/20180808/GIF/4179-19-5.gif)
4179-19-5
148 suppliers
$6.00/1g
![5-Chloro-1,3-dimethoxybenzene](/CAS/GIF/7051-16-3.gif)
7051-16-3
188 suppliers
$10.00/1g
![Methylmagnesium Bromide](/CAS/GIF/75-16-1.gif)
75-16-1
263 suppliers
$12.00/10ml
![3,5-Dimethoxytoluene](/CAS/20180808/GIF/4179-19-5.gif)
4179-19-5
148 suppliers
$6.00/1g