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(3,5-DIMETHYL-1H-PYRAZOL-4-YL)ACETIC ACID synthesis

3synthesis methods
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Yield:32701-75-0 12%

Reaction Conditions:

with hydrazine hydrate in methanol at 20; for 3 h;

Steps:



General procedure: Ester Hydrolysis To a solution of the ester (1.0 eq.) in methanol (1.4 mL mmol"1) was added hydrazine monohydrate (1.5 eq.) and the reaction stirred at room temperature for 3 h. Reaction mixture was concentrated under reduced pressure, yielding carboxylic acid without further purification.

References:

WO2013/83991,2013,A1 Location in patent:Page/Page column 64

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