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ChemicalBook CAS DataBase List 3-Amino-1-methylpyridin-2(1H)-one

3-Amino-1-methylpyridin-2(1H)-one synthesis

2synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1.1: sodium hydride / tetrahydrofuran / 0.5 h
1.2: 16 h / 55 °C / Inert atmosphere
2.1: hydrogen; palladium 10% on activated carbon / 16 h / Sonication; Inert atmosphere

References:

Loughlin, Wendy A.;Jenkins, Ian D.;Karis, N. David;Healy, Peter C. [European Journal of Medicinal Chemistry,2017,vol. 127,p. 341 - 356]