![](/CAS/GIF/28314-81-0.gif)
3-bromo-2,6-difluorobenzoic acid synthesis
- Product Name:3-bromo-2,6-difluorobenzoic acid
- CAS Number:28314-81-0
- Molecular formula:C7H3BrF2O2
- Molecular Weight:237
![1,3-Difluorobenzene](/CAS/GIF/372-18-9.gif)
372-18-9
411 suppliers
$9.00/1g
![3-bromo-2,6-difluorobenzoic acid](/CAS/GIF/28314-81-0.gif)
28314-81-0
114 suppliers
$7.00/100mg
Yield:-
Steps:
Multi-step reaction with 3 steps
1: 94 percent / butyllithium; bromine / hexane; tetrahydrofuran / 0.75 h / -75 °C
2: diisopropylamine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C
3: 96 percent / 2,2,6,6-tetramethylpiperidine; butyllithium / hexane; tetrahydrofuran / 2 h / -75 °C
References:
Schlosser, Manfred;Heiss, Christophe [European Journal of Organic Chemistry,2003,# 23,p. 4618 - 4624]
![1-Bromo-2,4-difluorobenzene](/CAS/GIF/348-57-2.gif)
348-57-2
414 suppliers
$5.00/5g
![Carbon dioxide](/CAS/GIF/124-38-9.gif)
124-38-9
121 suppliers
$175.00/23402
![3-bromo-2,6-difluorobenzoic acid](/CAS/GIF/28314-81-0.gif)
28314-81-0
114 suppliers
$7.00/100mg
![1-Bromo-2,6-difluorobenzene](/CAS/GIF/64248-56-2.gif)
64248-56-2
273 suppliers
$6.00/1g
![Carbon dioxide](/CAS/GIF/124-38-9.gif)
124-38-9
121 suppliers
$175.00/23402
![3-bromo-2,6-difluorobenzoic acid](/CAS/GIF/28314-81-0.gif)
28314-81-0
114 suppliers
$7.00/100mg
![1-Bromo-2,6-difluorobenzene](/CAS/GIF/64248-56-2.gif)
64248-56-2
273 suppliers
$6.00/1g
![3-bromo-2,6-difluorobenzoic acid](/CAS/GIF/28314-81-0.gif)
28314-81-0
114 suppliers
$7.00/100mg
![1-Bromo-2,4-difluorobenzene](/CAS/GIF/348-57-2.gif)
348-57-2
414 suppliers
$5.00/5g
![Carbon dioxide](/CAS/GIF/124-38-9.gif)
124-38-9
121 suppliers
$175.00/23402
![3-bromo-2,6-difluorobenzoic acid](/CAS/GIF/28314-81-0.gif)
28314-81-0
114 suppliers
$7.00/100mg
![2,4-Difluorobenzoic acid](/CAS/GIF/1583-58-0.gif)
1583-58-0
413 suppliers
$6.00/5g
![2,6-Difluorobenzoic acid](/CAS/GIF/385-00-2.gif)
385-00-2
414 suppliers
$5.00/5g