3-Bromo-2-oxopropanoyl chloride synthesis
- Product Name:3-Bromo-2-oxopropanoyl chloride
- CAS Number:75261-25-5
- Molecular formula:C3H2BrClO2
- Molecular Weight:185.4
1113-59-3
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75261-25-5
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Yield:75261-25-5 95%
Reaction Conditions:
with Dichloromethyl methyl ether at 20 - 50; for 2.5 h;
Steps:
1
1, 1-Dichlorodimethyl ether (2.5g. 21 ,74 mmol) was added slowly to solid Bromopyruvic acid (1) while maintaining the temperature below 2.0C. The resulting slurry was slowly heatedto 5WC and stIrred lix 2.5 it The. clear solution was cooled and the excess of dichlorodim.ethyi ether was concentrated under vacuum to obtain 3-bromopyruvic chloride (2) in greater than 95%yield.
References:
WO2018/102412,2018,A1 Location in patent:Page/Page column 11
1113-59-3
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$14.00/1g
4885-02-3
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$10.00/1g
75261-25-5
4 suppliers
$140.68/250mgs: