![](/CAS/GIF/766-82-5.gif)
3-Ethynyltoluene synthesis
- Product Name:3-Ethynyltoluene
- CAS Number:766-82-5
- Molecular formula:C9H8
- Molecular Weight:116.16
![3-[(Trimethylsilyl)ethynyl]toluene](/CAS2/GIF/40230-90-8.gif)
40230-90-8
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![3-Ethynyltoluene](/CAS/GIF/766-82-5.gif)
766-82-5
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Yield:766-82-5 93%
Reaction Conditions:
with potassium trimethylsilonate in dimethyl sulfoxide at 60; under 760.051 Torr; for 7 h;Catalytic behavior;Sealed tube;Reagent/catalyst;Solvent;
Steps:
20
3-[(trimethylsilyl)ethynyl]toluene (1 mmol), inorganic base potassium tert-butoxide (sodium) or potassium hydroxide (sodium) or potassium trimethylsilylate (sodium) (0.05 mmol), 2 mL of DMA or DMSO solvent was sequentially added to a 10 mL sealed tube, and the mixture was heated and stirred in a 60°C oil bath for 7 hours. The progress of the reaction was followed by TLC. The reaction was completed and an equivalent of mesitylene or n-undecane was added as a crude product. The exact yield of the product was determined by GC and GC-MS. According to GC and GC-MS, when DMSO is used as a reaction solvent, inorganic base potassium tert-butoxide (sodium) or potassium hydroxide (sodium) or potassium trimethylsilylate (sodium) is used as a catalyst, and the yields of the products are as follows: : 74%, 73%, 74%, 80%, 93%, 90%. When DMA was used as the reaction solvent, the inorganic potassium tert-butoxide (sodium) or potassium hydroxide (sodium) or potassium trimethylsilylate (sodium) was used as the catalyst. The yield of the product was: 61%, 60%, respectively. 63%, 73%, 82%, 83%.
References:
Taizhou University;Yao Wubing CN107459438, 2017, A Location in patent:Paragraph 0054; 0055
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591-17-3
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1066-54-2
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$9.00/10g
![3-Ethynyltoluene](/CAS/GIF/766-82-5.gif)
766-82-5
170 suppliers
$20.00/1g
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625-95-6
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$14.00/25g
![3-Ethynyltoluene](/CAS/GIF/766-82-5.gif)
766-82-5
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![3-Butyn-2-ol, 2-methyl-4-(3-methylphenyl)-](/CAS/20180601/GIF/63079-66-3.gif)
63079-66-3
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![3-Ethynyltoluene](/CAS/GIF/766-82-5.gif)
766-82-5
170 suppliers
$20.00/1g
![3-Iodotoluene](/CAS/GIF/625-95-6.gif)
625-95-6
252 suppliers
$14.00/25g
![Trimethylsilylacetylene](/CAS/GIF/1066-54-2.gif)
1066-54-2
468 suppliers
$9.00/10g
![3-Ethynyltoluene](/CAS/GIF/766-82-5.gif)
766-82-5
170 suppliers
$20.00/1g