3-HYDROXYBENZOPHENONE synthesis
- Product Name:3-HYDROXYBENZOPHENONE
- CAS Number:13020-57-0
- Molecular formula:C13H10O2
- Molecular Weight:198.22
? in the presence of 10% Pd/C in refluxing xylene for 6 h (60%)
? in the presence of lithium bromide and cupric bromide in refluxing acetonitrile for 1 h (75%).
1711-05-3
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$8.00/1g
13020-57-0
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$9.00/250mg
6136-67-0
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$45.00/20mg
Yield: 78%
Reaction Conditions:
aluminium chloride in benzene
Steps:
a Synthesis of 3-hydroxybenzophenone. (R1 =R2 =R3 =H) (II)
EXAMPLE a Synthesis of 3-hydroxybenzophenone. (R1 =R2 =R3 =H) (II) 0.1 mole of m-methoxybenzoyl chloride and 0.11 mole of aluminium chloride are refluxed for 8 hours in 100 ml of benzene. An oily product is formed, which is distilled (198° C./13 mm Hg). Yield: 60%. 0.1 mole of the 3-methoxybenzophenone thus obtained is heated under reflux for 9 hours in 100 ml of 48% hydrobromic acid. When the hydrolysis is finished the product obtained is recrystallized in a mixture of equal volumes of water and alcohol. Yield: 78%. Melting point of the product obtained: 118° C.
References:
Unicler US4277497, 1981, A
6136-67-0
28 suppliers
$45.00/20mg
13020-57-0
124 suppliers
$9.00/250mg
1016-77-9
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$10.00/1g
13020-57-0
124 suppliers
$9.00/250mg
100-83-4
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$5.00/10g
98-80-6
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$5.00/5g
13020-57-0
124 suppliers
$9.00/250mg
25116-37-4
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$263.00/250mg
13020-57-0
124 suppliers
$9.00/250mg