ChemicalBook CAS DataBase List 3-METHYL-1-CYCLOHEXENE

3-METHYL-1-CYCLOHEXENE synthesis

14synthesis methods

Product Name:3-METHYL-1-CYCLOHEXENE
CAS Number:591-48-0
Molecular formula:C7H12
Molecular Weight:96.17

110-05-4 Synthesis

110-05-4
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$23.00/100mL

110-83-8
304 suppliers
$11.00/25g

591-48-0
60 suppliers
$108.00/25mL

1541-20-4
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Yield:1541-20-4 35 %Chromat.

Reaction Conditions:

with α,α,α-trifluorotoluene;cobalt(II) chloride at 120; for 24 h;Inert atmosphere;Molecular sieve;Sealed tube;Glovebox;

Steps:

Oxidation of 2a in the absence of 1a

Each reaction was prepared under argon atmosphere with a PhCF3 solution (3 mL) consisting of DTBP (567 μL, 3.0 mmol), 2a (1536 μL, 15.0 mmol, 5.0 equiv.), and molecular sieves (4A, 495.0 mg) in each sealed reaction tube with a stirbar. To this solution, 0, 0.25/1.0 (mol%/mg), 0.5/2.0 (mol%/mg), 0.75/2.9 (mol%/mg) or 1.0/3.9(mol%/mg) of CoCl2 was added, respectively. The resulted mixture was then heated up to 120 °C and reacted for 24 h. Each reaction was sampled and analyzed by GC with biphenyl as internal standard.

References:

Ren, Tian-Lu;Xu, Bao-Hua;Mahmood, Sajid;Sun, Ming-Xue;Zhang, Suo-Jiang [Tetrahedron,2017,vol. 73,# 20,p. 2943 - 2948] Location in patent:supporting information

201230-82-2 Synthesis