ChemicalBook CAS DataBase List 3-METHYL-2(3H)-BENZOTHIAZOLONE

3-METHYL-2(3H)-BENZOTHIAZOLONE synthesis

11synthesis methods

Product Name:3-METHYL-2(3H)-BENZOTHIAZOLONE
CAS Number:2786-62-1
Molecular formula:C8H7NOS
Molecular Weight:165.21

934-34-9 Synthesis

934-34-9
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$10.00/1g

2786-62-1
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$60.00/50mg

Yield:2786-62-1 100%

Reaction Conditions:

with tetrabutylammomium bromide;dimethyl sulfate in sodium hydroxide;water;toluene;

Steps:

37 EXAMPLE 37

EXAMPLE 37 Benzothiazolone (3.78 g, 0.025 mole) was dissolved in a solution of sodium hydroxide (1.60 g, 0.0375 mole) in water (100 c.c.), and tetra-n-butylammonium bromide (0.24 g, 7.5*10^-4 mole) and toluene (40 c.c.) were added thereto. Dimethyl sulfate (4.70 g, 0.0375 mole) was added dropwise thereto at room temperature, and the mixture was stirred at room temperature for 1 hour, followed by phase-separation. The toluene layer was washed once with water, and the solvent was removed under reduced pressure to obtain 4.14 g of N-methylbenzothiazolone as white crystals. Yield 100%, purity 97.7%, m.p. 70°-73.5° C.

References:

US4293702,1981,A

95-16-9 Synthesis