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ChemicalBook CAS DataBase List 3-Pyrrolidin-3-ylpyridine

3-Pyrrolidin-3-ylpyridine synthesis

3synthesis methods
-

Yield:150281-46-2 69%

Steps:

W 3-(3-Pyrrolidinyl)pyridine

Example W 3-(3-Pyrrolidinyl)pyridine Starting from 3-[1-(phenylmethyl)-3-pyrrolidinyl]pyridine (5.00 g, 21.0 mmol), a procedure analogous to that described in Example V provided the title compound (2.15 g, 69%) as a pale orange oil. 1 H NMR (250 MHz, d6 DMSO): δ=1.60-1.75 (1H, m), 2.08-2.29 (1H, m), 2.58-2.69 (1H, m), 2.85-3.04 (2H, m), 3.07-3.36 (2H, m), 7.31 (1H, dd, J=7.9, 4.9 Hz), 7.69 (1H, d, J=7.9 Hz), 8.39 (1H, d, J=4.9 Hz), 8.48 (1H, s).

References:

US5221676,1993,A

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