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ChemicalBook CAS DataBase List 4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZOIC ACID

4-(1H-1,2,4-TRIAZOL-1-YLMETHYL)BENZOIC ACID synthesis

3synthesis methods
-

Yield:-

Steps:

Multi-step reaction with 2 steps
1: 1.) 18-crown-6, KOC(CH3)3 / 1.) THF, 15 min; 2.) THF, 2 h at 0°C then overnight at room temp.
2: 57 percent / 10percent aq. KOH / ethanol / 3 h / Heating

References:

Silvestri;Pagnozzi;Valoti;Fusi [Il Farmaco,1994,vol. 49,# 10,p. 625 - 632]