Welcome to chemicalbook!
Chinese English Japanese Germany Korea
400-158-6606
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

4-[(3-TRIFLUOROMETHYL)PHENYL]-1-BUTENE synthesis

7synthesis methods
-

Yield:21172-36-1 262 mg

Reaction Conditions:

Stage #1: Methyltriphenylphosphonium bromidewith n-butyllithium in tetrahydrofuran;hexane at 0; for 0.5 h;Inert atmosphere;
Stage #2: 3-[3-(trifluoromethyl)phenyl]propanal in tetrahydrofuran;hexane at -78 - 20;Inert atmosphere;Wittig Olefination;

References:

Nouaille, Augustin;Pannecoucke, Xavier;Poisson, Thomas;Couve-Bonnaire, Samuel [Advanced Synthesis and Catalysis,2021,vol. 363,# 8,p. 2140 - 2147] Location in patent:supporting information