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80523-79-1

4,4'-DIBROMODIPHENYL-D8 synthesis

4synthesis methods
-

Yield:80523-79-1 75%

Reaction Conditions:

Stage #1: 1,4-dibromotetradeuterobenzenewith tert.-butyl lithium in tetrahydrofuran at -78; for 1.5 h;
Stage #2: with copper(l) cyanide in tetrahydrofuran at -78 - 20;
Stage #3: with 2,5-Dimethyl-1,4-benzoquinone in tetrahydrofuran at 20; for 3 h;

References:

Obrien, Zachary J.;Karlen, Steven D.;Khan, Saeed;Garcia-Garibay, Miguel A. [Journal of Organic Chemistry,2010,vol. 75,# 8,p. 2482 - 2491] Location in patent:experimental part

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