![](/CAS/GIF/40877-09-6.gif)
4,4'-DICHLOROBUTYROPHENONE synthesis
- Product Name:4,4'-DICHLOROBUTYROPHENONE
- CAS Number:40877-09-6
- Molecular formula:C10H10Cl2O
- Molecular Weight:217.09
![4-CHLOROPHENYLMAGNESIUM BROMIDE](/CAS/GIF/873-77-8.gif)
873-77-8
142 suppliers
$42.60/100ml
![4-Chlorobutyryl chloride](/CAS/GIF/4635-59-0.gif)
4635-59-0
465 suppliers
$17.39/10g
![4,4'-DICHLOROBUTYROPHENONE](/CAS/GIF/40877-09-6.gif)
40877-09-6
64 suppliers
$5.00/1g
Yield: 90%
Reaction Conditions:
Stage #1:4-Chlorobutanoyl chloride with 1-methyl-pyrrolidin-2-one in toluene at 0; for 0.5 h;
Stage #2:(4-chlorphenyl)magnesium bromide in tetrahydrofuran;toluene at -10 - 0; for 4.25 h;chemoselective reaction;
References:
Gowda, Maravanhalli Sidde;Pande, Sushanth Sudhir;Ramakrishna, Ramesha Andagar;Prabhu, Kandikere Ramaiah [Organic and Biomolecular Chemistry,2011,vol. 9,# 15,p. 5365 - 5368] Location in patent:supporting information; experimental part
![1-(4-Chlorophenyl)cyclobutanol](/CAS/20200401/GIF/29480-09-9.gif)
29480-09-9
4 suppliers
inquiry
![4,4'-DICHLOROBUTYROPHENONE](/CAS/GIF/40877-09-6.gif)
40877-09-6
64 suppliers
$5.00/1g
![Chlorobenzene](/CAS/GIF/108-90-7.gif)
108-90-7
644 suppliers
$10.00/25G
![4-Chlorobutyryl chloride](/CAS/GIF/4635-59-0.gif)
4635-59-0
465 suppliers
$17.39/10g
![4,4'-DICHLOROBUTYROPHENONE](/CAS/GIF/40877-09-6.gif)
40877-09-6
64 suppliers
$5.00/1g
![1-Chloro-4-iodobenzene](/CAS/GIF/637-87-6.gif)
637-87-6
286 suppliers
$38.00/10 G
![4-Chlorobutyryl chloride](/CAS/GIF/4635-59-0.gif)
4635-59-0
465 suppliers
$17.39/10g
![4,4'-DICHLOROBUTYROPHENONE](/CAS/GIF/40877-09-6.gif)
40877-09-6
64 suppliers
$5.00/1g